Author(s): Sujitha S, Sindhu R, Prabu D, Rajmohan M, Dinesh Dhamodhar

Email(s): researchphdsrm@gmail.com

DOI: 10.52711/2321-5828.2024.00005   

Address: Sujitha S, Sindhu R, Prabu D*, Rajmohan M, Dinesh Dhamodhar
Professor and Head, Dept. of Public Health Dentistry, Public Health Forum, Ramapuram, Chennai - 89, Tamil Nadu, India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 1,     Year - 2024


ABSTRACT:
As water quality degradation worsens in many countries, economic growth is stunted, health conditions worsen, food production is reduced, and poverty is exacerbated. The aim is to study the quantified levels of carcinogens in the environment, according to IARC Classification such as Arsenic, Cadmium, Chromium, Nickel, Lead, Nitrite/Nitrate and Phosphates and its correlation with spurts of cancer cases across certain sites that lie along Thamirabharani river basin, Tamil Nadu, India. A Systematic literature review for cross-sectional studies that provided information about the groundwater quality was carried out using six databases, "Researchgate, PubMed, Elsevier science direct, Wiley Online Library, Medline and Springerlink" from 2005 to 2021. TNCRP 2021 was taken as a reference to analyze the percentage of all types of cancer cases reported in the districts that lie along the river basin. Quality assessment was done using Newcastle Ottawa Scale. The results show the presence of high concentration of carcinogens in the groundwater and sediments collected near the industries, agricultural land and municipal sewage yard. The significant association between exceeding of the permissible limit of various heavy metal elements and compounds and percentage of cancer cases at that particular site is established in this study. Oral findings commonly associated with chronic toxicity of carcinogenic heavy metals are listed which serves as an alarming signal to adapt to healthy lifestyle and dietary modifications as required.


Cite this article:
Sujitha S, Sindhu R, Prabu D, Rajmohan M, Dinesh Dhamodhar. An Analysis of Cancer causing Substances and its Impact on Prevalence of Cancer Cases among General Population residing along Thamirabharani River Basin – Evidence based research. Research Journal of Humanities and Social Sciences. 2024;15(1)24-0. doi: 10.52711/2321-5828.2024.00005

Cite(Electronic):
Sujitha S, Sindhu R, Prabu D, Rajmohan M, Dinesh Dhamodhar. An Analysis of Cancer causing Substances and its Impact on Prevalence of Cancer Cases among General Population residing along Thamirabharani River Basin – Evidence based research. Research Journal of Humanities and Social Sciences. 2024;15(1)24-0. doi: 10.52711/2321-5828.2024.00005   Available on: https://rjhssonline.com/AbstractView.aspx?PID=2024-15-1-5


REFERENCES:
1.    Press release: Worsening Water Quality Reducing Economic Growth by a Third in Some Countries: World Bank. The World Bank: IBRD-IDA. (Accessed on: August 20, 2023). https://www.worldbank.org/en/news/press-release/2019/08/20/worsening-water-quality-reducing-economic-growth-by-a-third-in-some-countries
2.    Progress on household drinking water, sanitation and hygiene; 2000-2020. WHO | UNICEF JMP. https://data.unicef.org/resources/progress-on-household-drinking-water-sanitation-and-hygiene-2000-2020/ (Accessed on August 23, 2023).
3.    Sampath P., Swaminathan R on behalf of the TNCRP Study Group. 2021. Cancer incidence and mortality (Year 2017), incidence trend (2012-2017) and estimates (2018-2021) for Tamil Nadu state. Tamil Nadu Cancer Registry Project, Cancer Institute (W.I.A), Chennai, Tamil Nadu, India.
4.    Sujitha S, Prabu D, Dinesh Dhamodhar, Rajmohan M, Sindhu R. An analysis of cancer causing agents and its association with the prevalence of cancer cases in Noyyal river basin, Tamil Nadu, India - A Explorative study based on scientific evidences. Int J Health Sci Res. 2023; 13(9):1-13.
5.    World Health Organisation. 2022 IARC list of carcinogens. IARC Monographs Volumes 1-132. https://monographs.iarc.who.int/list-of-classifications/
6.    World Health Organisation. 2022. List of classifiacations by cancer sites with sufficient or limited evidence in humans, IARC Monographs Volumes 1-132 https://monographs.iarc.who.int/wp-content/uploads/2019/07/Classifications_by_cancer_site.pdf
7.    Prabudoss Kumar L, Ramkumar J, Jesu A, Dheenadayalan MS. A correlation study of heavy metal in Thamirabarani river region at Tirunelveli district, Tamilnadu. International Journal of Research and Analytical Reviews. 2019; 6(1):15-19.
8.    Mathivanan V, Sangeetha V, Uma Maheswari D, Selvisabhanayakam. Environmental pollution monitoring studies on Thambiraparani river at Tirunelveli district, Tamil Nadu. International Journal of Current Research. 2013; 5(10):3001-3007.
9.    Divya Sapphire M, Sabaridasan., Jesslin G., Edwin Thangam P., Soranam R. Analysis of water quality parameters and heavy metals concentration from the selected sites of Tamiraparani river, Tirunelveli district, Tamilnadu, India. International Research Journal of Environment Sciences. 2016; 5(7): 47-54.
10.    Nawab Ali SS, Mohamed Sihabudeen M, Syed Abuthahir SS. Study of heavy metal pollution in groundwater near proximity of Thamirabharani river, Tamil Nadu, India. International Journal of Biology, Pharmacy and Allied Sciences. 2021; 10(11): 296-304.
11.    Sivakumar Karthikeyan, Shanmugasundaram Arumugam, Jayaprakash Muthumanickam, Prabakaran Kulandaisamy, Muthusamy Subramanian, Ramachandran Annadurai et al. Causes of heavy metal contamination in groundwater of Tuticorin Industrial block, Tamil Nadu, India. Environmental Science and Pollution Research. 2021; 28: 18651-18666.
12.    Kayalvizhi A, Evany Nithya S. Assessment of heavymetal in and around the industrial zone of Tuticorin. International Journal of Engineering Research and Technology. 2019; 7(2): 1-5.
13.    Puthiyasekar C, Neelakantan MA, Poongothai S. Heavy metal contamination in bore water due to industrial pollution and polluted and non-polluted sea water intrusion in Thoothukudi and Tirunelveli of South Tamil Nadu, India. Bulletin of Environmental Contamination Toxicology. 2010; 85:598-601.
14.    Sajimol Sundar, Priyadarsi D. Roy, Lakshumanan Chokkalingam, Nagarajan Ramasamy. Evaluation of metals and trace elements in sediments of Kanyakumari beach (southernmost India) and their possible impact on coastal aquifiers. Marine Pollution Bulletin. 2021; 169: 112527.
15.    Malathi J, Brahmanandhan GM, Khanna D, Selvasekarapandian S. Study of primordial radionuclide distribution in sand samples of Agastheeswaran taluk of Kanyakumari district, India. International Congress Series-Elsevier. 2005; 1276:321-322.
16.    Toxicology profiles. Agency for Toxic Substances and Disease Registry. U.S. Department of Health and Human Services. Last Reviewed: May 3, 2023
17.    Raschida R Bouhouch, Sana El-Fadeli, Maria Andersson, Abdelmounaim Aboussad, Laila Chabaa and Christophe Zeder et al. Effects of wheat-flour biscuits fortified with iron and EDTA, alone and in combination, on blood lead concentration, iron status, and cognition in children: a double-blind randomized controlled trial. American Journal Clinical Nutrition. 2016; 104:1318–26.
18.    Geir Bjørklund, Shiblur Rahaman, Mariia Shanaida Roman Lysiuk, Petro Oliynyk and Larysa Lenchyk et al. Natural Dietary Compounds in the treatment of Arsenic Toxicity. Molecules. 2022; 27(15): 4871.
19.    Regina M. Krohn, Rubhana Raqib, Evana Akthar, Albert Vandenberg and Judit E.G. Smits. A high selenium lentil dietary intervention in Bangladesh to counteract arsenic toxicity: study protocol for a randomized controlled trial. BioMed Central. Trials. 2016; 17(21)
20.    Pankaj B. Bhogam, Sushant A. Gharal, Tushar B. Patil, Aarti A. Varne, Priyanka S. Lad. A Systematic Review on Anticancer Phytosomal Flavonoids. Asian Journal of Research in Pharmaceutical Sciences. 2023; 13(4): 343-6. doi: 10.52711/2231-5659.2023.00059
21.    Kanchan R. Pagar, Sarika V. Khandbahale, D. G. Phadtare. The Therapeutic Potential of Resveratrol: A Review of Clinical Trials. Asian J. Pharm. Res. 2019; 9(3): 193-199. doi: 10.5958/2231-5691.2019.00031.5
22.    Surya Rajeev Nair, Shreelakshmi, Bharathwaj, Sindhu.R, Rajmohan and Prabu.D et al. Systematic review on the use of Indian Gooseberry in improvement of oral hygiene. Drug and Cell Therapies in Hematology. 2021; 10(1): 2611–2620.
23.    Tirunelveli councilors demand measures to halt sewage inflow into Thamirabarani river. The Hindu – Madurai. Dated on: May 29, 2023. https://www.thehindu.com/news/cities/Madurai/tirunelveli-councilors-demand-measures-to-halt-sewage-inflow-into-thamirabarani-river/article66907658.ece
24.    Preeti Sinha. Phytoremediation Techniques. Research Journal of Pharmacy and Technology. 2022; 15(11): 5359-2. doi: 10.52711/0974-360X.2022.00903
25.    Damini D, Sukriti P, C.Subathra Devi, E. Selvarajan, V. Suganthi, V. Mohanasrinivasan. Removal of Heavy Metals from Leather Industry Effluent Using Saccharomyces sp In a Packed Bed Reactor. Research J. Engineering and Tech. 2013; 4(2): 53-56
26.    Alok Awasthi. Bio- accumulation of Cd, Cr, Cu, Ni and Pb in a wild grass, Parthenium hysterophorus L. Asteraceae, growing naturally on barren land and evaluation of phyto-extraction potential of the plant for studied metals. Asian Journal of Research in Chemistry. 2023; 16(4): 277-4. doi: 10.52711/0974-4150.2023.00046
27.    G.V. Krishna Mohan, S. R. Wate. The Assessment of Heavy Metal Concentrations in Phytoremediation Species of Sonneratia caseolaris, Tropical Dry Evergreen Forests of Peninsular India. Asian J. Research Chem. 2011; 4(5): 741-745
28.    Elakiya Sugumaran, Prashanthy MR, Bharathwaj VV, Prabu D, SunayanaManipal and Rajmohan. Glyphosate, Phorate, and Monocrotophos Hazardous Pesticide Usage and Its Public Health Impact – An Empirical Analysis. Indian Journal of Forensic Medicine and Toxicology. 2021; 15(5): 156–161.
29.    Alekh Kumar Sahu, Dolamani Sahu. Role of Education in Controlling of Environmental Pollution. Int. J. Rev. and Res. Social Sci. 2013; 1(1): 27-28
30.    Kelvin Kibet, Esther W. Nthiga, Moses A. Ollengo. Removal of Cd2+ and Cr3+ ions from Aqueous Solution by Modified Polypropylene Plastic Waste: Equilibrium Study. Asian Journal of Research in Chemistry. 2023; 16(5): 349-7. doi: 10.52711/0974-4150.2023.00056
31.    Hassan T Abdulsahib, Abdulamir H Taobi, Salah S Hashem. A Novel Adsorbent Based on Lignin and Tannin for the Removal of Heavy Metals from Wastewater. Res. J. Pharmacognosy and Phytochem. 2015; 7(1): 38-48. doi: 10.5958/0975-4385.2015.00009.6
32.    Kaushal Patidar, Ankita Chaudhari. A Study to Assess the Effectiveness of Planned Teaching Programe on Knowledge regarding prevention of Lung Cancer among Industrial Workers in selected Industry of Mehsana District.Asian J. Nursing Education and Research. 2019; 9(3):346-348. doi: 10.5958/2349-2996.2019.00074.0

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